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An ionizable cationic lipid has been used in the generation of LNPs for mRNA delivery in vivo LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein increase anti-spike glycoprotein IgG titers in the BALF as well as increase the percentage of CD8 CD8 CD44 CD4 and CD4 CD44 T cells in the lungs and spleen in mice after two doses three weeks apart LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein inhibit reductions in body weight increase serum levels of anti-spike glycoprotein IgG and IgA titers and reduce lung and nasal wash viral titers in a hamster model of SARS-CoV-2 Omicron BQ.1 subvariant infection
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An ionizable cationic lipid has been used in the generation of LNPs for mRNA delivery in vivo LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein increase anti-spike glycoprotein IgG titers in the BALF as well as increase the percentage of CD8 CD8 CD44 CD4 and CD4 CD44 T cells in the lungs and spleen in mice after two doses three weeks apart LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein inhibit reductions in body weight increase serum levels of anti-spike glycoprotein IgG and IgA titers and reduce lung and nasal wash viral titers in a hamster model of SARS-CoV-2 Omicron BQ.1 subvariant infection
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More